Acetohydroxamic Acid

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Absorption Well absorbed from the GI tract following oral administration.
Volume of distribution Not Available
Protein binding No known binding
Metabolism
35-65% of oral dose excreted unchanged in urine (which provides the drug's therapeutic effect).
Route of elimination Not Available
Half life 5-10 hours in patients with normal renal function
Clearance Not Available
Toxicity Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
Affected organisms
  • Enteric bacteria and other eubacteria
Pathways Not Available

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