Adinazolam

Absorption	Not Available
Volume of distribution	Not Available
Protein binding	Not Available
Metabolism	Hepatic. The main metabolite is N-desmethyladinazolam. The other two metabolites are alpha-hydroxyalprazolam and estazolam. Enzyme Metabolite Reaction Km Vmax Cytochrome P450 3A4 desmethyladinazolam N-demethylation 83 0 Cytochrome P450 2C19 desmethyladinazolam N-demethylation 39 0
Route of elimination	Not Available
Half life	Less than 3 hours.
Clearance	Not Available
Toxicity	Signs of overdose may include muscle weakness, ataxia, dysarthria and particularly in children paradoxical excitement. In more severe cases diminished reflexes, confusion, and coma may ensue.
Affected organisms	Humans and other mammals
Pathways	Not Available