Aminophenazone

0 comments
Absorption Not Available
Volume of distribution Not Available
Protein binding Not Available
Metabolism
Enzyme Metabolite Reaction Km Vmax
Cytochrome P450 2D6 N-Desmethylaminopyrine N-demethylation

Cytochrome P450 1A2 N-Desmethylaminopyrine N-demethylation

Cytochrome P450 3A4 N-Desmethylaminopyrine N-demethylation

Cytochrome P450 2C9 N-Desmethylaminopyrine N-demethylation

Cytochrome P450 2C8 N-Desmethylaminopyrine N-demethylation

Cytochrome P450 2C19 N-Desmethylaminopyrine N-demethylation

Cytochrome P450 2C18 N-Desmethylaminopyrine N-demethylation

Route of elimination Not Available
Half life Not Available
Clearance Not Available
Toxicity Can cause life-threatening agranulocytosis.
Affected organisms
  • Humans and other mammals
Pathways Not Available

0 comments:

Post a Comment

Copyright 2011 Pharmacokinetics of Drugs.
Blogger Template by Noct.