Antipyrine

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Absorption Not Available
Volume of distribution Not Available
Protein binding Not Available
Metabolism
Enzyme Metabolite Reaction Km Vmax
Cytochrome P450 1A2 Norantipyrine demethylation

Cytochrome P450 1A2 3-Hydroxymethylantipyrine 3-hydroxylation

Cytochrome P450 1A2 4-Hydroxyantipyrine 4-hydroxylation

Cytochrome P450 3A4 4-Hydroxyantipyrine 4-hydroxylation

Cytochrome P450 2C9 Norantipyrine demethylation

Cytochrome P450 2C9 3-Hydroxymethylantipyrine 3-hydroxylation

Cytochrome P450 2C8 Norantipyrine demethylation

Cytochrome P450 2C19 Norantipyrine demethylation

Route of elimination Not Available
Half life Not Available
Clearance Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals

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