Absorption | Well absorbed following subcutaneous administration, with a mean bioavailability of 92% (based on anti-factor Xa activity). |
Volume of distribution | Not Available |
Protein binding | Not Available |
Metabolism | Liver and the reticulo-endothelial system are the sites of biotransformation. |
Route of elimination | Not Available |
Half life | Elimination half-life for anti-factor Xa activity averages 3.3 hours following a single intravenous dose, while elimination half-life for anti-factor IIa activity averages 1.2 hours following a single intravenous dose. |
Clearance | Not Available |
Toxicity | Symptoms of overdose may include excessive bleeding and bruising. |
Affected organisms |
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Ardeparin
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