Azlocillin

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Absorption Not significantly absorbed from the gastrointestinal tract.
Volume of distribution Not Available
Protein binding 20 to 46% bound to plasma proteins
Metabolism
Eliminated predominantly by renal mechanisms, but also undergoes biotransformation within body tissues and intraintestinal degradation by bowel bacteria, with high concentrations found in bile.
Route of elimination Not Available
Half life Mean elimination half-life is 1.3 to 1.5 hours. Longer in neonates, and 2 to 6 hours in patients with renal impairment.
Clearance Not Available
Toxicity Not Available
Affected organisms
  • Enteric bacteria and other eubacteria

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